Patient-reported symptom burden and impact on daily activities in chronic graft-versus-host disease (Cancer Medicine, November 2022, Jingbo et al)

165 qualifying GvHD patients were surveyed about their symptom burden and ability to perform activities of daily living.

There are limited patient-reported data concerning symptom burden and effects on activities of daily living (ADL).

Yes! This is understudied and under-appreciated in dry eye more broadly. It is also the focus of large 480-patient community survey’s section on “Quality of Life” (see mydryeyedata.org for more).

So here are some of their key results:

44% of respondents considered "dry eye" the most burdensome symptom. Almost half of respondents (n = 73 [44.2%]) rated their overall quality of life (QoL) as poor. Participants reported a detrimental impact of symptoms on ADL, including basic activities (eg, eating, personal hygiene, dressing).

And their conclusions:

Conclusions: Survey respondents self-reported high chronic GVHD symptom burden and felt that their symptoms severely interfered with physical function and ADL. Effective strategies to mitigate chronic GVHD symptoms are needed to improve QoL among HSCT survivors.